Covering of open wounds with skin is accomplished by transposition of skin in the form of a graft or flap, or skin transplantation in full or partial thickness. Certain risk always exists since such a procedure is inevitably characterized by insufficient supply of the transplanted tissue with blood and/or oxygen. Therefore, the procedure will fail in certain number of cases.

HBOT enhances damage to the transplanted tissue caused by lower concentration of oxygen (hypoxia/ischemia), ameliorates microcirculation and lowers thrombocyte aggregation, increases number and size of blood vessels in microcirculation (ideal preparation of surgical site), fastens production of healthy granulation tissue, stimulates activity of fibroblasts and synthesis of collagen.

blood transplanted tissue skin transplantation ischemia microcirculation oxygen